System Integration of the LabPET Small Animal PET Scanner

TitleSystem Integration of the LabPET Small Animal PET Scanner
Publication TypeConference Paper
Year of Publication2006
AuthorsTetrault, M. - A., N. Viscogliosi, J. Riendeau, F. Belanger, J. B. Michaud, H. Semmaoui, P. Berard, F. Lemieux, L. Arpin, J. Cadorette, C. M. Pepin, G. Robert, M. D. Lepage, R. Lecomte, and R. Fontaine
Conference NameNuclear Science Symposium Conference Record, 2006. IEEE
Pagination1880 -1884
Date Publishedoct.
Keywords16.2 cm, 45 MHz, automatic channel calibration, avalanche photodiodes, biomedical equipment, data acquisition boards, data recording, data transfers, digital positron emission tomography scanner, digital signal analysis, Firewire link, gated image reconstruction, LabPET, medical computing, phoswich array, positron emission tomography, small animal PET scanner, sorting tree, system integration, time synchronized data insertion

To address modern molecular imaging requirements, a digital positron emission tomography scanner for small animals has been developed at Universite de Sherbrooke. Based on individual readout of avalanche photodiodes (APD) coupled to a LYSO/LGSO phoswich array, the scanner supports up to 3072 channels in a 16.2 cm diameter, 7.5 cm axial field of view with an isotropic 1.2 mm FWHM intrinsic spatial resolution at the center of the FOV. Custom data acquisition boards sample APD signals at 45 MHz and compute in real time crystal identification, energy and timing information of detected events at rates of up to 1250 raw counts per second per mm2 (10k cps/channel). Real time digital signal analysis also filters out events outside the photopeak with crystal granularity to eliminate Compton events and electronic noise. Retained events are then merged into a single stream through a real-time sorting tree, at which end the prompt and delayed coincidences are extracted. A single Firewire link handles both control and data transfers with a computer. The LabPETtrade features four data recording modes, giving the user the choice to retain data for research or to minimize file size for high coincidence count rate and imaging purposes. The electronic system also supports time synchronized data insertion for flags such as vital signs used in gated image reconstruction. Aside from data acquisition, hardware can generate live energy and discrimination histograms suitable for fast, automatic channel calibration.


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