Estimating Arterial Stiffness using Transmission Line Model

TitleEstimating Arterial Stiffness using Transmission Line Model
Publication TypeConference Paper
Year of Publication2006
AuthorsLeung, M., G. Dumont, G. G. S. Sandor, and J. E. Potts
Conference NameEngineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE
Pagination1375 -1378
Date Publishedaug.
Keywords2-D echocardiography, aortic root diameter measurement, applanation tonometry, arterial stiffness index, ascending aorta, biomechanics, blood flow measurement, blood pressure measurement, blood vessels, cardiovascular system, distributive compliance, Doppler measurement, echocardiography, grey-box identification, parameter estimation, physiological models, transmission line model, ultrasonic measurement, wave propagation, wave reflection

An arterial stiffness index based on the transmission line model is defined. The parameters of the transmission line model are initially estimated using measured pressure, flow and aortic root diameter. Pressure is measured at the carotid using applanation tonometry. Flow is measured using Doppler at the ascending aorta. Aortic root diameter is measured using 2-D echocardiography. The initial estimates are then refined using grey-box identification. The resulting estimate of the distributive compliance of the transmission line model is proposed to be an arterial stiffness index. Similar to the Windkessel compliance, this index describes the global stiffness. However, it is based on a more realistic 1-D model that can simulate wave propagation and wave reflection


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