[Closed-loop titration of propofol guided by the bispectral index]

Title[Closed-loop titration of propofol guided by the bispectral index]
Publication TypeJournal Article
Year of Publication2007
AuthorsLiu, N., T. Chazot, B. Trillat, G. A. Dumont, and M. Fischler
JournalAnn Fr Anesth Reanim
Volume26
Pagination850-4
Date PublishedOct
Abstract

This review analyzes the clinical studies concerning the automated perfusion, or closed-loop, of propofol guided by the bispectral index (BIS). To carry out the maintenance of general anaesthesia by a closed loop propofol-BIS is feasible as shown by studies comprising few low risk patients. We showed that induction of anaesthesia is feasible with a closed loop, haemodynamic stability being similar to a manual titration. A second study, bearing on the whole of the anaesthesia of patients ASA I to III undergoing very diverse surgical acts, showed that the closed loop propofol-BIS was more precise than a manual perfusion. This confirms that the closed loop propofol-BIS is not an esoteric research and that it represents a tool with a future for the clinician.

URLhttp://dx.doi.org/10.1016/j.annfar.2007.06.013
DOI10.1016/j.annfar.2007.06.013

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