Ion channels - estimation and control at macroscopic and nano scales

TitleIon channels - estimation and control at macroscopic and nano scales
Publication TypeConference Paper
Year of Publication2004
AuthorsKrishnamurthy, V.
Conference NameControl Conference, 2004. 5th Asian
Pagination42 - 50 Vol.1
Date Publishedjul.
Keywordsbiocontrol, bioelectric phenomena, biology, biomembrane transport, electrical activities, gating problem, hidden Markov model signal processing, hidden Markov models, ion channel control, ion channel estimation, macroscopic scale, membrane ion channel, molecular level, nanoscale, nervous system, optimisation, permeation problem, physiological models, stochastic control, stochastic optimization, stochastic processes, stochastic systems
Abstract

All electrical activities in the nervous system, including communications between cells and the influence of hormones and drugs on cell function, are regulated by membrane ion channels. Therefore understanding their mechanisms at a molecular level is a fundamental problem in biology. This paper shows how ideas in hidden Markov model signal processing, stochastic control and stochastic optimization can be used to understand the operation of ion channels at both a macroscopic and nano scales.

URLhttp://dx.doi.org/10.1109/ASCC.2004.184743
DOI10.1109/ASCC.2004.184743

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